A study has explored the influence of 3 key factors for periodontal disease-smoking, diabetes and genetics. Researchers determined that patients with genetic variations of the IL-1 genotype or one or more other risk factors were at significantly increased risk for tooth loss and thus require more preventive dental care.
Periodontitis is a bacterially induced chronic inflammatory disease that destroys the bone and gum tissues that support the teeth. It causes bleeding and swelling of the gums, bad breath, loose teeth and can eventually lead to tooth loss. Severe periodontitis has been linked to increased risk of diseases like cardiovascular diseases, diabetes and rheumatoid arthritis.
Genetic testing can identify patients who have an increased inflammatory response to oral bacteria which significantly increase the risk of periodontitis and tooth loss. Thus it is imperative such patients seek early preventive dental care.